邵稳

职称：教授

性别：男

职务：

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电子邮箱：shaowen@xtu.edu.cn

课题组主页：https://www.x-mol.com/groups/shaowen

工作学习经历

主讲课程

《有机化学》、《有机化学实验》、《金属有机化学》、《文献与专业英语》

研究方向 

过渡金属不对称催化；功能分子和材料精准构筑；高分子聚合物催化降解

个人简介 

邵稳，博士，特聘教授，硕士生导师，省“百人计划”特聘专家。2012年于同济大学获得理学学士学位，2017年于中国科学院上海有机化学研究所获得理学博士学位（导师：游书力 院士）。2017-2020年先后于德国马普煤炭研究所和瑞士日内瓦大学开展博士后科学研究。于2021年1月加入亚洲菠菜十大平台推荐，从事功能有机分子催化合成以及废塑料催化降解研究。先后主持国家自然科学基金青年项目、湖南省自然科学基金青年项目、湖南省教育厅优秀青年项目、湖南省高层次创新团队项目子课题等多项科研项目，以第一作者或通讯作者在J. Am. Chem. Soc., Angew. Chem. Int. Ed., ACS Catal., Green Chem., Chin. Chem. Lett., Org. Lett.等国际高水平期刊发表SCI论文20余篇，申请中国发明专利六项。

主要学术成果 

科研论文：

1. Xuan Zhou, Xi Hu, Yi Chen, Hongxing Zhu, Muyang Yang, Guo-Jun Deng, Wen Shao,* Copper-Catalysed Radical Amino-Oxygenation of Alkenes for the Exclusive Synthesis of 5-Substituted 2-Oxazolidinones. Green Chem. 2025, DOI: 10.1039/D5GC00917K. (Highlighted by "雁城方法学")

2. Jianhua Ji,† Kangjie Li,† Xiangzhu Zhou, Chun Xu, Die Zhang, Wen Shao,* Visible-Light Organophotoredox-Catalyzed Fluoroalkyl Aminoxylation of Unactivated and Activated Alkenes. Chem. Commun. 2025, DOI: 10.1039/D5CC00748H. (†co-first authors), ("2025 Emerging Investigators" Themed Collection)

3. Silin Huang,† Yue Cui,† Boqiang Wang,† Fang-Jie Liu, Jia-Yi Liu, Wen Shao,* Xue-Qiang Wang,* Qiang Guo,* Bisboronic Ester-Enabled Redox-Targeted Cancer Therapy: A Cascade ROS Consumption Approach for Efficient Elimination of Cancer Cells. J. Med. Chem. 2025, 68, 6656-6664. (†co-first authors)

4. Xiyao Chen, Wen Shao,* Guo-Jun Deng,* Nickel-Catalyzed Deoxygenative Disulfuration of Alcohols to Access Unsymmetrical Disulfides. ACS Catal. 2024, 14, 6451-6461. (Highlighted by "化学深耕堂"，"有机那点事")

5. Boqiang Wang,† Yongzhuo Xu,† Jiajia Wang,* Muyang Yang, Guo-Jun Deng,* Wen Shao,* Transition-Metal Free Trifluoromethylimination of Alkenes Enabled by Direct Activation of N-Unprotected Ketimines. Chin. Chem. Lett. 2024, 35, 109502. (†co-first authors)

6. Shuowen Wang,† Rong Li,† Shanping Chen, Guojiang Mao, Wen Shao,* Guo-Jun Deng,* Chemoselective Synthesis of α‑Carboline Derivatives via Hypervalent Iodine-Catalyzed [3+3] Annulation under Metal-Free Conditions, Green Synth. Catal. 2024, 5, 112-116. (†co-first authors)

7. Yongzhuo Xu, Boqiang Wang, Jiajia Wang,* Xuan Zhou, Jiaxing Chen, Xinjia Guo, Guo-Jun Deng,* Wen Shao,* Regioselective Synthesis of Unsymmetrical Vicinal Diamines via Azidoimination of Alkenes with TMSN₃ and Ketimines. Org. Lett. 2023, 25, 8716-8721. (Highlighted by "Organic Chemistry Portal")

8. Muyang Yang, Wen Shao,* Lin, Zuo, Jiajia Wang, Yongzhuo Xu, Guojiang Mao, Guo-Jun Deng,* Site-Selective Radical Trifluoromethylaminoxylation of Olefins for Modular Synthesis of Diverse β-Trifluoromethyl Trisubstituted Hydroxylamines and Beyond. Org. Lett. 2023, 25, 2728-2732.

9. Yongzhuo Xu, Jiajia Wang,* Guo-Jun Deng, Wen Shao,* Recent Advances in the Synthesis of Chiral α-Tertiary Amines via Transition-Metal Catalysis, Chem. Commun. 2023, 59, 4099-4114.

10. Qihua Wu, Weixian Zhang, Wen Shao*, Yong Pei,* Jiajia Wang,* Partially Bio-Based and Fluorinated Polysiloxane with High Transparency and Low Dielectric Constant, Eur. Polym. J. 2023, 194, 112136.

11. Shuowen Wang, Rong Li, Huawen Huang, Guojiang Mao, Wen Shao,* Guo-Jun Deng,* Substrate-Dependent Divergent Oxyamination of beta-Tetralones Enabling Modular Synthesis of 2-Amino-para- Iminonaphthoquinones and 4-Amino-1,2-Naphthoquinone Derivatives, Adv. Syn. Catal. 2023, 365, 1449-1456.

12. Jiaxing Chen,† Yongzhuo Xu,† Wen Shao,* Jianhua Ji, Boqiang Wang, Muyang Yang, Guojiang Mao, Fuhong Xiao,* Guo-Jun Deng,* Pd-Catalyzed C−O Bond Formation Enabling the Synthesis of Congested N,N,O‑Trisubstituted Hydroxylamines, Org. Lett. 2022, 24, 8271-8276. (†co-first authors)

13. Shuowen Wang, Rong Li, Shuxin Jiang, Huawen Huang, Wen Shao,* Guo-Jun Deng,* Selective Synthesis of Diverse Heterocycles via Metal-Free Oxidative Coupling of beta-Tetralone and Nitrogen Nucleophiles, Adv. Syn. Catal. 2022, 364, 1481-1487.

14. Wen Shao, Céline Besnard, Laure Guénée, Clément Mazet,* Ni-Catalyzed Regiodivergent and Stereoselective Hydroalkylation of Acyclic Branched Dienes with Unstabilized C(sp3) Nucleophiles, J. Am. Chem. Soc. 2020, 142, 16486-16492. (Selected as JACS Spotlights)

15. Wen Shao, Qing-Feng Xu-Xu, Shu-Li You,* Highly Diastereoselective Synthesis of Polycyclic Indolines through Formal [4+2] Propargylic Cycloaddition of Indoles with Ethynyl Benzoxazinanones, Chem. Asian J. 2020, 15, 2462-2466.

16. Wen Shao, Marcel Lux, Martin Breugst, Martin Klussmann,* Radical Addition of Ketones and Cyanide to Olefins via Acid Catalyzed Formation of Intermediate Alkenyl Peroxides, Org. Chem. Front. 2019, 6, 1796-1800.

17. Wen Shao, Ye Wang, Ze-Peng Yang, Xiao Zhang, Shu-Li You,* Efficient Synthesis of N-Alkylated 4-Pyridones by Copper-Catalyzed Intermolecular Asymmetric Propargylic Amination, Chem. Asian J. 2018, 13, 1103-1107.

18. Wen Shao, Shu-Li You,* Highly Diastereo- and Enantioselective Synthesis of Tetrahydro-5H-Indolo[2,3-b]quinolines through Copper-Catalyzed Propargylic Dearomatization of Indoles, Chem. Eur. J. 2017, 23, 12489-12493.

19. Wen Shao, He Li, Chuan Liu, Chen-Jiang Liu,* Shu-Li You,* Copper-Catalyzed Intermolecular Asymmetric Propargylic Dearomatization of Indoles, Angew. Chem. Int. Ed. 2015, 54, 7684-7687. (Highlighted by Chin. J. Org. Chem. 2015, 35, 1802)

20. Ze-Peng Yang, Qing-Feng Wu, Wen Shao, Shu-Li You,* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Pyridines, Pyrazines, Quinolines and Isoquinolines, J. Am. Chem. Soc. 2015, 137, 15899-15906.

21. Gaël Tran, Wen Shao, Clément Mazet,* Ni-Catalyzed Enantioselective Intermolecular Hydroamination of Branched 1,3-Dienes Using Primary Aliphatic Amines, J. Am. Chem. Soc. 2019, 141, 14814-14822.

科研项目：

1. 国家自然科学基金青年项目，22201239，2023-2025，主持

2. 湖南省自然科学基金青年项目，2022JJ40429，2022-2024，主持

3. 湖南省教育厅优秀青年项目，21B0130，2021-2024，主持

4. 湖南省“过程强化与绿色化工”创新团队项目，2022-2025，主持子课题

5. BR计划-10大信誉菠菜担保平台配套经费，21QDZ24，2021-2026，主持

荣誉奖励：

1. 2025年，第五届湖南省普通高校教师教学创新大赛，校三等级

2. 2024年，10大信誉菠菜担保平台教师课堂教学竞赛暨课程思政教学比赛，三等级

3. 2022年，入选湖南省海外高层次引才“百人计划团队”

4. 2022年，入选10大信誉菠菜担保平台韶峰学者“青年拔尖人才计划”

5. 2021年，入选湖南省青年“百人计划”

欢迎有志于有机合成与催化科学研究的优秀学生报考，每年可招收2-4名硕士研究生；同时欢迎本科生加入本课题组开展长期科研训练！